Table 2 Potential therapeutic small molecular compounds from connectivity map (CMap) website based on GIRPI
CMap name | Mean | N | Enrichment | P-value | Specificity | Percent non-null |
|---|---|---|---|---|---|---|
Resveratrol | − 0.616 | 9 | − 0.769 | <0.00001 | 0.0093 | 88 |
15-Delta prostaglandin J2 | − 0.327 | 15 | − 0.627 | <0.00001 | 0.0301 | 60 |
6-Bromoindirubin-3ʹ-oxime | − 0.445 | 7 | − 0.81 | 0.00002 | 0 | 71 |
Methotrexate | − 0.414 | 8 | − 0.717 | 0.00012 | 0.0069 | 62 |
Butoconazole | − 0.643 | 4 | − 0.852 | 0.00092 | 0.0076 | 100 |
Prestwick-984 | − 0.403 | 4 | − 0.831 | 0.00147 | 0.0056 | 75 |
Puromycin | − 0.475 | 4 | − 0.804 | 0.00284 | 0.0448 | 75 |
5707885 | − 0.236 | 4 | − 0.788 | 0.00406 | 0.0168 | 50 |
Bergenin | − 0.342 | 4 | − 0.772 | 0.00547 | 0.0065 | 50 |