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  1. Orthopaedic and trauma research is a gateway to better health and mobility, reflecting the ever-increasing and complex burden of musculoskeletal diseases and injuries in Germany, Europe and worldwide. Basic sc...

    Authors: Henning Madry, Susanne Grässel, Ulrich Nöth, Borna Relja, Anke Bernstein, Denitsa Docheva, Max Daniel Kauther, Jan Christoph Katthagen, Rainer Bader, Martijn van Griensven, Dieter C. Wirtz, Michael J. Raschke and Markus Huber-Lang

    Citation: European Journal of Medical Research 2021 26:56

    Content type: Review

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  2. Central retinal artery occlusion (CRAO) is an emergent ophthalmic disease which is commonly caused by atherosclerosis, thromboembolism, and arteriospasm. Here, we report a case of CRAO which is caused by extre...

    Authors: Lanbing Zhu, Na Xu and Yan Li

    Citation: European Journal of Medical Research 2021 26:55

    Content type: Case report

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  3. We are laryngologists. We observe natural phonatory and swallowing functions in clinical examinations with a trans-nasal laryngeal fiberscope (TNLF). Before each observation, we use epinephrine to enlarge and ...

    Authors: Koichi Tsunoda, Ko Hentona and Yoshiharu Yamanobe

    Citation: European Journal of Medical Research 2021 26:52

    Content type: Case report

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  4. Coronavirus Disease-2019 (SARS-CoV-2) started its devastating trajectory into a global pandemic in Wuhan, China, in December 2019. Ever since, several variants of SARS-CoV-2 have been identified. In the presen...

    Authors: SeyedAhmad SeyedAlinaghi, Pegah Mirzapour, Omid Dadras, Zahra Pashaei, Amirali Karimi, Mehrzad MohsseniPour, Mahdi Soleymanzadeh, Alireza Barzegary, Amir Masoud Afsahi, Farzin Vahedi, Ahmadreza Shamsabadi, Farzane Behnezhad, Solmaz Saeidi, Esmaeil Mehraeen and Shayesteh Jahanfar

    Citation: European Journal of Medical Research 2021 26:51

    Content type: Review

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  5. This study is aimed to analyze the prognostic factors affecting the short-term efficacy of non-surgical treatment of patients in periodontitis from stage II to stage IV by the multilevel modeling analysis.

    Authors: Hui-Jie Liu, Bo Wang, Ao-Chen Wang, Dan-Hong Zhang, Cui Mao and Qiu-Hong Li

    Citation: European Journal of Medical Research 2021 26:50

    Content type: Research

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  6. Glomus tumor is an uncommon soft tissue tumor. However, as the tumor causes significant disability, its early diagnosis is essential. It involves subungual areas of fingers and toes in most cases, and its extr...

    Authors: Leila Oryadi Zanjani, Bahman Shafiee Nia, Farzad Vosoughi, Elham Mirzaian, Leila Aghaghazvini and Aidin Arabzadeh

    Citation: European Journal of Medical Research 2021 26:49

    Content type: Case report

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  7. Pulmonary sequestration (PS) associated with massive hemoptysis, hemothorax, and elevated tumor markers or even lung malignancy has been reported in several studies. These clinical features combined with lung ...

    Authors: Wei Luo, Tong-chen Hu, Lincheng Luo and Ya-lun Li

    Citation: European Journal of Medical Research 2021 26:48

    Content type: Case report

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  8. COVID-19 is a worldwide pandemic and has placed significant demand for acute and critical care services on hospitals in many countries.

    Authors: Saad Alhumaid, Abbas Al Mutair, Zainab Al Alawi, Khulud Al Salman, Nourah Al Dossary, Ahmed Omar, Mossa Alismail, Ali M. Al Ghazal, Mahdi Bu Jubarah, Hanan Al Shaikh, Maher M. Al Mahdi, Sarah Y. Alsabati, Dayas K. Philip, Mohammed Y. Alyousef, Abdulsatar H. Al Brahim, Maitham S. Al Athan…

    Citation: European Journal of Medical Research 2021 26:47

    Content type: Research

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  9. While COVID-19 pandemic continues to spread worldwide, researchers have linked patterns of traits to poor disease outcomes. Risk factors for COVID-19 include asthma, elderly age, being pregnant, having any und...

    Authors: SeyedAhmad SeyedAlinaghi, Mohammad Mehrtak, Mehrzad MohsseniPour, Pegah Mirzapour, Alireza Barzegary, Pedram Habibi, Banafsheh Moradmand-Badie, Amir Masoud Afsahi, Amirali Karimi, Mohammad Heydari, Esmaeil Mehraeen, Omid Dadras, Jean-Marc Sabatier and Fabricio Voltarelli

    Citation: European Journal of Medical Research 2021 26:46

    Content type: Review

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  10. Hematological comparison of coronavirus disease (COVID-19) and other viral pneumonias can provide insights into COVID-19 treatment.

    Authors: Bingke Bai, Zhe Xu, Yan Hu, Mengmeng Qu, Juan Cheng, Shengdong Luo, Zengtao Yao, Hongyan Gao, Yenv Ma, Rong Gao, Jun Hou, Shaojie Xin and Panyong Mao

    Citation: European Journal of Medical Research 2021 26:45

    Content type: Research

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  11. Tarlov cysts are a commonly misdiagnosed condition, which can present with many rare symptoms. We report a case of a Tarlov cyst with spermatorrhea and review the pertinent literature.

    Authors: Pan Sun, Wangbing Xu, Yongxiang Ye, Faming Zhong, Xuan Wan and Yong Li

    Citation: European Journal of Medical Research 2021 26:44

    Content type: Case report

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  12. Degeneration of the intervertebral discs are very common diseases, indicating the specific or malignant changes in intervertebral disc component, structure and function. Imaging examination is currently used t...

    Authors: Tiefang Liu, Yonghao Wang, Zhengyang Xu, Tao Wu, Xiao Zang, Meng Li and Jinfeng Li

    Citation: European Journal of Medical Research 2021 26:43

    Content type: Research

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  13. Enchondromas originating in the epiphyses of long bones are rare and epiphyseal osteoid osteomas are also uncommon. Diagnosis can become elusive when enchondromas or osteoid osteomas occur in atypical location...

    Authors: Xuyang Cao, Qiang Ren, Xiangnan Li, Yiren Tian and Zhendong Wang

    Citation: European Journal of Medical Research 2021 26:42

    Content type: Case report

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    The Correction to this article has been published in European Journal of Medical Research 2021 26:53

  14. The clinical course of COVID-19 may vary significantly. The presence of comorbidities prolongs the recovery time. The recovery in patients with mild-to-moderate symptoms might take 10 days, while in those with...

    Authors: SeyedAhmad SeyedAlinaghi, Ladan Abbasian, Mohammad Solduzian, Niloofar Ayoobi Yazdi, Fatemeh Jafari, Alireza Adibimehr, Aazam Farahani, Arezoo Salami Khaneshan, Parvaneh Ebrahimi Alavijeh, Zahra Jahani, Elnaz Karimian, Zahra Ahmadinejad, Hossein Khalili, Arash Seifi, Fereshteh Ghiasvand, Sara Ghaderkhani…

    Citation: European Journal of Medical Research 2021 26:41

    Content type: Research

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  15. The purpose of this article is to summarize the epidemiologic characteristics and double-buffered strategy for patients in orthopedic surgery during the COVID-19 outbreak in Wuhan, China, based on our own expe...

    Authors: Yan Zhou, Jianghua Ming and Shiqing Liu

    Citation: European Journal of Medical Research 2021 26:39

    Content type: Research

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  16. Multiple organ dysfunction syndrome (MODS) and the consecutive multiple organ failure (MOF) are severe and dreaded complications with a high mortality in multiple trauma patients. The aim of this study was to ...

    Authors: Julian Haupt, Niels Krysiak, Marina Unger, Viktoria Bogner-Flatz, Peter Biberthaler, Marc Hanschen, Martijn van Griensven and Alexander T. Haug

    Citation: European Journal of Medical Research 2021 26:38

    Content type: Research

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  17. Due to limited antibiotic options, carbapenem-resistant Enterobacteriaceae (CRE) infections are associated with high non-relapse mortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT). ...

    Authors: Fengqin Su, Yi Luo, Jian Yu, Jimin Shi, Yanmin Zhao, Mengni Yan, He Huang and Yamin Tan

    Citation: European Journal of Medical Research 2021 26:37

    Content type: Case report

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  18. Surgery-related loss of muscle quantity negatively affects postoperative outcomes. However, changes of muscle quality have not been fully investigated. A perioperative intervention targeting identified risk fa...

    Authors: Laura van Wijk, Stijn van Duinhoven, Mike S. L. Liem, Donald E. Bouman, Alain R. Viddeleer and Joost M. Klaase

    Citation: European Journal of Medical Research 2021 26:36

    Content type: Research

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  19. The Abbreviated Injury Scale (AIS) and Injury Severity Score (ISS) are widely used to assess trauma patients. In this study, the interobserver variability of the injury severity assessment for severely injured...

    Authors: Eftychios Bolierakis, Sylvia Schick, Kai Sprengel, Kai Oliver Jensen, Frank Hildebrand, Hans-Christoph Pape and Roman Pfeifer

    Citation: European Journal of Medical Research 2021 26:35

    Content type: Research

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  20. Rosai–Dorfman–Destombes (RDD) is also known as sinus histiocytosis with massive lymphadenopathy (SHML). It is a benign proliferative disorder of histiocytes, affecting lymph nodes, rarely with extra-nodal invo...

    Authors: Santosh Tummidi, Hemant Kumar Singh, Prudhvinath A Reddy, Manda Sindhura, Navya Kosaraju, Arundhathi Shankaralingappa and Naresh P Kumar

    Citation: European Journal of Medical Research 2021 26:34

    Content type: Case report

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  21. In children, up to 30% of viral respiratory tract infections (RTIs) develop into bacterial complications associated with pneumonia, sinusitis or otitis media to trigger a tremendous need for antibiotics. This ...

    Authors: Mercedes Ogal, Sebastian L. Johnston, Peter Klein and Roland Schoop

    Citation: European Journal of Medical Research 2021 26:33

    Content type: Research

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  22. The aim of this study was to assess the treatment outcomes of multidrug and extensively drug-resistant tuberculosis (M/XDR-TB) in Zhejiang, China and to evaluate possible risk factors associated with poor outc...

    Authors: Ming-Wu Zhang, Lin Zhou, Yu Zhang, Bin Chen, Ying Peng, Fei Wang, Zheng-Wei Liu, Xiao-Meng Wang and Song-Hua Chen

    Citation: European Journal of Medical Research 2021 26:31

    Content type: Research

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  23. Despite modern advances in intensive care medicine and surgical techniques, mortality rates in cardiac surgical patients are still about 3%. Considerable efforts were made to predict morbidity and mortality af...

    Authors: Andreas Bauer, Insa Korten, Gerd Juchem, Isabel Kiesewetter, Erich Kilger and Jens Heyn

    Citation: European Journal of Medical Research 2021 26:29

    Content type: Research

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  24. AdipoR2, which belongs to the seven-transmembrane-domain receptor family, has been shown to play an important role in the development of human tumours, but the underlying mechanisms are poorly understood. In t...

    Authors: Chen Jie, Wang Xuan, Han-Dong Feng, Ding-Mao Hua, Wang Bo, Sun Fei and Zhang Hao

    Citation: European Journal of Medical Research 2021 26:28

    Content type: Research

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  25. Compliance with the surviving sepsis campaign (SSC) guidelines (Cssc) is a key factor affecting the effects of sepsis treatment. We designed this study to investigate the relationships of the structure indicators...

    Authors: Lu Wang, Xudong Ma, Huaiwu He, Longxiang Su, Yanhong Guo, Guangliang Shan, Xiang Zhou, Dawei Liu and Yun Long

    Citation: European Journal of Medical Research 2021 26:27

    Content type: Research

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  26. Inadequate activation of the innate immune system after trauma can lead to severe complications such as Acute Respiratory Distress Syndrome and Multiple Organ Dysfunction Syndrome. The spleen is thought to mod...

    Authors: Michel Paul Johan Teuben, Arne Hollman, Taco Blokhuis, Roman Pfeifer, Roy Spijkerman, Henrik Teuber, Hans-Christoph Pape and Luke Petrus Hendrikus Leenen

    Citation: European Journal of Medical Research 2021 26:26

    Content type: Research

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  27. The incidence of post-traumatic osteoarthritis (PTOA) after anterior cruciate ligament reconstruction (ACLR) is high, but there is still a lack of intra-operative preventive measures. This study aimed to evalu...

    Authors: Xinghui Liu, Rong Chen, Liangbo Jiang, Xiangwei Li and Zhibo Sun

    Citation: European Journal of Medical Research 2021 26:24

    Content type: Research

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  28. Lung cancer is the fourth most common form of the tumor spreading to the bone. Among all patients of lung carcinoma, the most common sites of bone metastasis are vertebrae, ribs, and pelvis. By comparison, the...

    Authors: Karl Wu and Yu-Hao Huang

    Citation: European Journal of Medical Research 2021 26:23

    Content type: Case report

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  29. Citation analysis has been increasingly applied to assess the quantity and quality of scientific research in various fields worldwide. However, these analyses on spinal surgery do not provide visualization of ...

    Authors: Po-Hsin Chou, Yu-Tsen Yeh, Wei-Chih Kan, Tsair-Wei Chien and Shu-Chun Kuo

    Citation: European Journal of Medical Research 2021 26:22

    Content type: Research

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  30. Clubfeet and constriction band syndrome is a very rare non-idiopathic condition. Treatment is often difficult and the recurrence deformity rate is high. The purpose of this study was to assess the effectivenes...

    Authors: Bujar Shabani, Dafina Bytyqi and Cen Bytyqi

    Citation: European Journal of Medical Research 2021 26:21

    Content type: Case report

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  31. Vitamin C is an essential water-soluble nutrient that functions as a key antioxidant and has been proven to be effective for boosting immunity. In this study, we aimed to assess the efficacy of adding high-dos...

    Authors: Saeidreza JamaliMoghadamSiahkali, Besharat Zarezade, Sogol Koolaji, SeyedAhmad SeyedAlinaghi, Abolfazl Zendehdel, Mohammad Tabarestani, Ehsan Sekhavati Moghadam, Ladan Abbasian, Seyed Ali Dehghan Manshadi, Mohamadreza Salehi, Malihe Hasannezhad, Sara Ghaderkhani, Mohsen Meidani, Faeze Salahshour, Fatemeh Jafari, Navid Manafi…

    Citation: European Journal of Medical Research 2021 26:20

    Content type: Research

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  32. Diaphragmatic lesions as a result of blunt or penetrating trauma are challenging to detect in the initial trauma setting. This is especially true when diaphragmatic trauma is part of a polytrauma. Complication...

    Authors: Morris Beshay, Martin Krüger, Kashika Singh, Rainer Borgstedt, Tahar Benhidjeb, Edwin Bölke, Thomas Vordemvenne and Jan Schulte am Esch

    Citation: European Journal of Medical Research 2021 26:19

    Content type: Case report

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  33. Patients with severe COVID-19 have disorders of the respiratory, cardiovascular, coagulation, skeletal muscle, and central nervous systems. These systemic failures may be associated with cytokine release syndr...

    Authors: Nobutaka Chiba, Masakazu Matsuzaki, Takayuki Mawatari, Minori Mizuochi, Atsushi Sakurai and Kosaku Kinoshita

    Citation: European Journal of Medical Research 2021 26:18

    Content type: Case report

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  34. Ultrasonic measurement has not been utilized to assess the functional recovery of transplanted muscle. This study aimed to investigate the feasibility of using B-ultrasound measurement to assess muscle recover...

    Authors: Yi Hou, Jiantao Yang, Bengang Qin, Liqiang Gu and Jia Zheng

    Citation: European Journal of Medical Research 2021 26:17

    Content type: Research

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  35. Hypothermic machine perfusion (HMP) improves the quality of donor livers for transplantation, both in animal models and in clinical practice. Treatment with SP600125, an inhibitor of c-Jun N-terminal kinase (J...

    Authors: Yijie Zhang, Qi Pan, Ying Cheng and Yongfeng Liu

    Citation: European Journal of Medical Research 2021 26:15

    Content type: Research

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  36. Absence of cortical alignment in wedge-shaped and multifragmentary fractures (Fx) results in decreased fixation stability. The aim of this study was to compare the outcome using 2.0- vs. 3.5-mm screws for open...

    Authors: M. Wurm, M. Zyskowski, F. Greve, A. Gersing, P. Biberthaler and C. Kirchhoff

    Citation: European Journal of Medical Research 2021 26:14

    Content type: Research

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  37. Here, we report an atypical HIV-vacuolar myelopathy and search the available medical literature about atypical presentations of human immunodeficiency virus associate vacuolar myelopathy (HIV-VM) and immunoglo...

    Authors: Tau Mongezi, Joseph Sibi, George Jerry, Ibañez-Valdés Lourdes de Fátima, Dubula Tozama and Foyaca Sibat Humberto

    Citation: European Journal of Medical Research 2021 26:13

    Content type: Case report

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  38. Endometriosis is associated with a high number of chronic pelvic pain and reduced quality of life. Colorectal resections in case of bowel involvement of endometriosis are associated with an unneglectable morbi...

    Authors: Peter Tschann, Nikola Vitlarov, Martin Hufschmidt, Daniel Lechner, Paolo N. C. Girotti, Felix Offner, Burghard Abendstein and Ingmar Königsrainer

    Citation: European Journal of Medical Research 2021 26:12

    Content type: Research

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  39. Resuscitative endovascular balloon occlusion of the aorta (REBOA) may be used in severely injured patients with uncontrollable bleeding. However, zone-dependent effects of REBOA are rarely described. We compar...

    Authors: Sascha Halvachizadeh, Ladislav Mica, Yannik Kalbas, Miriam Lipiski, Marko Canic, Michel Teuben, Nikola Cesarovic, Zoran Rancic, Paolo Cinelli, Valentin Neuhaus, Hans- Christoph Pape and Roman Pfeifer

    Citation: European Journal of Medical Research 2021 26:10

    Content type: Research

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  40. This study attempts to evaluate the prognostic role of PHYH for overall survival (OS) in clear cell renal cell carcinoma (ccRCC) by means of publicly available data from The Cancer Genome Atlas (TCGA). Clinica...

    Authors: Qiu Zhengqi, Guo Zezhi, Jiang Lei, Qiu He, Pan Jinyao and Ao Ying

    Citation: European Journal of Medical Research 2021 26:9

    Content type: Research

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  41. More and more studies have confirmed that miRNAs play an important role in maintaining bone remodeling and bone metabolism. This study investigated the expression level of miR-206 in the serum of osteoporosis ...

    Authors: Zhiyuan Lu, Dawei Wang, Xuming Wang, Jilong Zou, Jiabing Sun and Zhenggang Bi

    Citation: European Journal of Medical Research 2021 26:8

    Content type: Research

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  42. The aim of this study was to detect the expression of interleukin (IL)-1β and transforming growth factor (TGF)-β1 in the colonic tissue and serum of irritable bowel syndrome (IBS) rats, as well as the distribu...

    Authors: Guanqun Chao, Zhaojun Wang, Xinli Chen and Shuo Zhang

    Citation: European Journal of Medical Research 2021 26:7

    Content type: Research

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