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Fig. 2 | European Journal of Medical Research

Fig. 2

From: Multi-omics and immunogenomics analysis revealed PFKFB3 as a targetable hallmark and mediates sunitinib resistance in papillary renal cell carcinoma: in silico study with laboratory verification

Fig. 2

Subclass clustering mediated by glycolysis-related genes and WGCNA. A Unsupervised consensus cluster analysis to determine two distinct subclasses mediated by glycolysis-related genes. B The glycolysis clusters, T classification, tumor stage, gender, survival status and age were used as patient annotations. C GSVA enrichment analysis of two glycolysis clusters. D Cluster dendrogram of all gene’s distribution based on a dissimilarity measure in WGCNA network. E Heatmap of the correlation between module eigengenes (MEs) and sample characteristic (Normal/Tumor) of pRCC. Each module contained the correlation coefficient and displayed in different colors. F A Venn diagram showing WGCNA-glycolysis-immune-related overlapping DEGs

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European Journal of Medical Research

ISSN: 2047-783X

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