Fig. 2From: The paradoxical role of cytokines and chemokines at the tumor microenvironment: a comprehensive reviewImmunosuppressive roles of cytokines and chemokines in TME. Cytokines and chemokines in the TME play several roles in immunosuppression during tumorigenesis. These include the recruitment of immunosuppressive cells such as MDSCs, Tregs, TAMs, TANs, etc., and inhibition of immune response from T cells and NK cellsBack to article page