Microbiota | Previous studies | The present study | |||
---|---|---|---|---|---|
Author | Year | Main findings | FBG | Blood lipids | |
Mitsuokella | Liu et al. [25] | 2021 | Mitsuokella was significantly dominant in the salivary microbiome for treatment-naive T2D patients | ↑a |  |
Palmas et al. [26] | 2021 | Mitsuokella from Firmicutes taxa was significantly increased in obese subjects, while Firmicutes taxa positively correlated with body fat and negatively with muscle mass | |||
Faecalibacterium | Yuan et al. [27] | 2022 | The serum uric acid level negatively associated with Faecalibacterium, which is one of the producers of short-chain fatty acids (SCFAs) | ↓b |  |
Ye et al. [28] | 2019 | The relative abundance of Faecalibacterium was lower in pregnant women with GD whose blood glucose failed to get control after lifestyle modifications | |||
The relative abundance of Faecalibacterium was negatively correlated with FBG | |||||
The peroxisome proliferator-activated receptor was positively correlated with the relative abundance of Faecalibacterium | |||||
Wu et al. [29] | 2020 | The abundance of Faecalibacterium sp were decreased in treatment-naive T2D patients | |||
Ferrocino et al. [46] | 2018 | Faecalibacterium was inversely correlated to FBG level in patients with GD | |||
Crusell et al. [10] | 2018 | Enrichment of species annotated to Faecalibacterium were showed in GD cohort compared with the normoglycaemic pregnant women | |||
Liu et al. [31] | 2020 | The gut microbiota of women with GD showed increased abundance of Faecalibacterium, and the relative abundance of Faecalibacterium was positively related to inflammatory factor concentrations | |||
Weissella | Huang et al. [32] | 2020 | Weissella cibaria MW01 could regulate inflammation through the NF-κB-mediated MLCK–pMLC pathway | ↑a |  |
Chen et al. [36] | 2022 | Weissella was found to be enriched in GD women who failed to respond to medical nutrition treatment for glycemic control | |||
Clostridium sensu stricto | MartÃnez-Cuesta et al. [47] | 2021 | The relative abundance of Clostridium sensu stricto was significantly diminished in obese individuals | ↑a |  |
Zeng et al. [37] | 2019 | Clostridium sensu stricto was positively related to waistline, BMI and serum lipid levels including LDL-C, TG and TC | |||
Maskarinec et al. [38] | 2021 | Clostridium sensu stricto was more abundant in T2D patients | |||
Crusell et al. [10] | 2018 | There was a depletion of species annotated to Clostridium sensu stricto in GD patients | |||
Corynebacterium | Nasim et al. [40] | 2021 | 11 species of Corynebacterium revealed a wide presence of toxins, multi-drug resistance and virulence factors, which are thought to be the source of infection in various diseases |  | ↑a |
Diphtheroid is the last common ancestor of all the Corynebacterium species | |||||
Li et al. [50] | 2021 | Serum/liver lipid and carbohydrate profiles were found strongly negatively correlated with Corynebacterium | |||
Rothia | Fatahi-Bafghi et al. [41] | 2021 | The genus Rothia are emerging as opportunistic pathogens associated with various infections, including endocarditis, pneumonia, peritonitis and, septicemia, abdominal infection, tonsillitis, spondylodiscitis, keratitis, meningitis, catheter-related infection, prosthetic device infection, osteomyelitis, peritoneal fluid, sputum, synovial fluid, bile, and bronchitis |  | ↑a |
Xu [42] | 2022 | Rothia might play an important role in alleviating atherosclerosis | |||
Granulicatella | Li et al. [43] | 2022 | Granulicatella was the independent risk factor for death of Hepatic encephalopathy after transjugular intrahepatic portosystemic shunt |  | ↑a |
Aranaz et al. [44] | 2021 | Granulicatella were more abundant in subjects with high inflammatory score | |||
Wu et al. [45] | 2018 | The abundance of Granulicatella in salivary microbiome was significantly increased in periodontally healthy obese people | |||
Crusell et al. [10] | 2018 | Granulicatella was a biomarker of GD | |||
Dong et al. [48] | 2021 | The abundance of Granulicatella in salivary microbiome was significantly higher in subjects with high serum TSH level (> 4.2 mIU/L) compared with subjects with normal TSH level (0.6–4.20 mIU/L) | |||
Zhao et al. [49] | 2020 | As a risk factor for the development of metabolic-associated fatty liver disease, insulin resistance was positively correlated with the abundance of Granulicatella in supragingival plaques |