Fig. 1

Bioinformatics analysis and clinical sample-based validation of the possible involvement of TASL with STAT3 in SLE. A, B GEO2R (A), GO and KEGG (B) analysis of the dataset; C PPI network constructed based on DEGs using the STRING database; D, E Expression (D) and correlation (E) analysis of TASL and STAT3 genes in the dataset; F, G TASL and STAT3 expression was detected (F) and correlation analysis was performed (G) based on the RNA extracted from PBMCs of healthy children and children with SLE (*P < 0.05, **P < 0.01)