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Table 2 Measurements of hemoglobin, iron parameters, and levels of hepcidin in schoolchildren with different iron scores

From: Circulating microRNAs and hepcidin as predictors of iron homeostasis and anemia among school children: a biochemical and cross-sectional survey analysis

Variables

Iron status

P-value

N I group (n = 250)

ID group (n = 50)

IDA group (n = 20)

IO group (n = 30)

Hepcidin (ng/ml)

68.6 ± 8.1

18.6 ± 6.1

14.6 ± 5.2

56.8 ± 3.7

0.001

Ferritin (ng/ml)

48.6 ± 15.7

32.6 ± 12.3

11.8 ± 6.9

9.5 ± 2.4

0.001

sTfR (nmol/L)

35.4 ± 7.4

52.9 ± 11.59

8.9 ± 3.1

7.1 ± 3.8

0.001

Transferrin saturation (%)

21.7 ± 6.5

13.9 ± 5.4

5.7 ± 3.8

19.5 ± 2.3

0.001

Iron (μg/dl)

91.6 ± 21.3

41.8 ± 3.4

21.5 ± 3.4

120.4 ± 31.4

0.001

TBIS

3.88 ± 1.1

2.6 ± 1.3

1.9 ± 0.85

7.6 ± 2.3

0.001

Hgb (g/dl)

13.2 ± 1.7

12.6 ± 2.1

8.6 ± 1.9

12.1 ± 2.7

0.001

  1. All values were reported as mean ± SD or median (interquartile range) or percentage. Significance was calculated by ANOVA followed by Student- Newman-Keul’s (SNK) post hoc pairwise comparison for age and metabolic parameters, or Chi-square test for residence and physical activity. Variables were considered significantly different at P < 0.05
  2. NI: normal iron (iron conc.; 75–175 μg/dl); ID: iron deficiency (iron conc.; < 75 μg/dl l); IDA: iron deficiency anemia (iron conc.; < 75 μg/dl l; hemoglobin < 120 g/L, and ferritin < 15 μg/L); IO: iron overload (iron conc.; ˃ 175 μg/dl); sTfR, soluble transferrin receptor; TBIS, total boy iron store; Hgb, hemoglobin