From: Ubiquitin-conjugating enzyme E2C (UBE2C) is a prognostic indicator for cholangiocarcinoma
Parameter | Category | Case No | UBE2C Expression | p-value | |
---|---|---|---|---|---|
Low | High | ||||
Gender | Male | 108 | 51 | 57 | 0.365 |
Female | 74 | 40 | 37 | Â | |
Age (years) |  < 65 | 107 | 51 | 56 | 0.451 |
 ≥ 65 | 75 | 40 | 35 |  | |
Hepatitis | Hepatitis B | 72 | 42 | 30 | 0.191 |
Hepatitis C | 29 | 13 | 16 | Â | |
Non-B, non-C | 81 | 36 | 45 | Â | |
Intrahepatic lithiasis | Not identified | 102 | 57 | 65 | 0.073 |
Present | 80 | 34 | 46 | Â | |
Surgical margin | R0 | 163 | 86 | 77 | 0.029* |
R1 | 19 | 5 | 14 | Â | |
Primary tumor (T) | T1 | 87 | 51 | 36 | 0.031* |
T2 | 61 | 29 | 32 | Â | |
T3 | 34 | 11 | 23 | Â | |
Histological variants | Large duct type | 105 | 41 | 64 | 0.001* |
Small duct type | 77 | 50 | 27 | Â | |
Histological Grade | Well differentiated | 61 | 35 | 26 | 0.023* |
Moderately differentiated | 66 | 37 | 29 | Â | |
Poorly differentiated | 55 | 19 | 36 | Â |