The clinical association between coagulation indexes, platelet-related parameters, and bone metastasis of newly diagnosed prostate cancer

Table 3 Detailed parameters of ROC curve

Parameter	AUC	Cutoff	Sensitivity (%)	Specificity (%)	P value
PLT (× 10⁹/L)	0.594	220	31.03	86.44	0.013
DD (mg/L)	0.790	2.5	63.79	81.36	< 0.001
Fib (g/L)	0.708	3.4	65.52	65.25	< 0.001
PSA(ng/ml)	0.846	59.74	66.38	89.83	< 0.001
PLT–DD	0.798	–	62.07	85.59	< 0.001
PLT–Fib	0.714	–	52.59	78.81	< 0.001
PLT–PSA	0.850	–	72.41	86.44	< 0.001
DD–Fib	0.829	–	71.55	85.59	< 0.001
DD–PSA	0.904	–	73.28	94.07	< 0.001
Fib–PSA	0.883	–	79.31	86.44	< 0.001
PLT–DD–Fib	0.837	–	75.86	81.36	< 0.001
DD–Fib–PSA	0.915	–	83.62	88.98	< 0.001
PLT–DD–Fib–PSA	0.915	–	83.62	89.00	< 0.001

PLT: platelet count; DD: D-dimer; Fib: fibrinogen; PLT–DD: the combination of platelet count and D-dimer; DD–Fib: the combination of D-dimer and fibrinogen; PLT–DD–Fib: the combination of platelet count; D-dimer and fibrinogen; PSA: prostate-specific antigen

ISSN: 2047-783X