The clinical association between coagulation indexes, platelet-related parameters, and bone metastasis of newly diagnosed prostate cancer

Table 1 Baseline characteristics of the study subjects

Parameter	Normal value range	Bone metastasis group (n = 116)	Non-bone metastasis group (n = 118)	t value	P value
Age (years)	–	71.87 ± 9.40	69.82 ± 7.62	− 1.833	0.068
BMI (kg/m²)	18.5 ~ 23.9	22.06 ± 1.65	22.38 ± 1.90	1.369	0.172
PLT (× 10⁹/L)	125 ~ 350	196.21 ± 46.78	180.78 ± 43.84	− 2.603	0.010
MPV (fL)	6 ~ 13	10.93 ± 1.39	11.08 ± 1.16	0.896	0.371
PDW (fL)	9 ~ 17	13.07 ± 2.98	13.50 ± 2.54	1.187	0.236
PCT (%)	0.108 ~ 0.282	0.19 ± 0.06	0.20 ± 0.04	0.927	0.355
DD (mg/L)	≦ 0.55	3.18 ± 1.53	1.70 ± 0.92	− 8.984	< 0.001
Fib (g/L)	2 ~ 4	3.94 ± 1.22	3.07 ± 0.95	− 6.100	< 0.001
APTT (s)	22 ~ 38	28.55 ± 5.56	27.81 ± 4.12	− 1.150	0.251
PT (s)	10 ~ 14	10.91 ± 1.30	10.70 ± 0.93	− 1.401	0.163
TT (s)	14 ~ 21	18.63 ± 2.50	19.18 ± 1.99	1.863	0.064
PSA (ng/ml)	0 ~ 4	72.41 ± 26.33	40.02 ± 15.84	− 11.422	< 0.001

BMI: Body Mass Index; PLT: platelet count; MPV: mean platelet volume; PDW: platelet distribution width; PCT: plateletcrit; DD: D-dimer; Fib: fibrinogen; APTT: activated partial thromboplastin time; TT: thrombin time; PT: prothrombin time; PSA: prostate-specific antigen

ISSN: 2047-783X