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Fig. 1 | European Journal of Medical Research

Fig. 1

From: CHKB-AS1 enhances proliferation and resistance to NVP-BEZ235 of renal cancer cells via regulating the phosphorylation of MAP4 and PI3K/AKT/mTOR signaling

Fig. 1

CHKB-AS1 participated in the formation of NVP-BEZ235 resistance. A, B IC50 suggested the construction of stably resistant 786-O and Caki-1 cell lines. C–E RNA-sequencing revealed the hub genes involved in the resistance. F CHKB-AS1 level in resistant and parental 786-O and Caki-1 cells. G Kaplan–Meier’s survival curves of ccRCC patients in low and high CHKB-AS1 groups. H CHKB-AS1 level in 32 paired ccRCC samples. I CHKB-AS1 level in HK-2 cells and ccRCC cells

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