Table 4 Odds ratio (95% confidence interval) for hypothyroidism according to the dietary pattern scores a
| Â | Tertile 1 | Tertile 2 | Tertile 3 | p-trend | Per SD | p value |
|---|---|---|---|---|---|---|
Clinical hypothyroidism | ||||||
 Native-based exploratory pattern | ||||||
  No. of participants | 1041 | 1041 | 1042 |  | 3124 |  |
  No. of cases | 38 | 39 | 56 |  | 133 |  |
  Unadjusted | 1.00 | 1.03 (0.65, 1.62) | 1.50 (0.98, 2.28) | 0.056 | 1.14 (0.95, 1.36) | 0.154 |
  Model 1 | 1.00 | 1.03 (0.65, 1.63) | 1.55 (1.01, 2.37) | 0.042 | 1.14 (0.96, 1.36) | 0.142 |
  Model 2 | 1.00 | 1.02 (0.62, 1.67) | 1.65 (1.04, 2.62) | 0.033 | 1.16 (0.95, 1.40) | 0.141 |
 EPIC-based exploratory pattern |  | |||||
  No. of participants | 1041 | 1041 | 1042 |  | 3124 |  |
  No. of cases | 43 | 42 | 46 |  | 133 |  |
  Unadjusted | 1.00 | 1.02 (0.67, 1.57) | 1.07 (0.70, 1.64) | 0.749 | 1.08 (0.91, 1.29) | 0.383 |
  Model 1 | 1.00 | 1.01 (0.65, 1.56) | 1.08 (0.70, 1.66) | 0.733 | 1.09 (0.91, 1.30) | 0.365 |
  Model 2 | 1.00 | 1.06 (0.66, 1.69) | 1.23 (0.77, 1.69) | 0.386 | 1.13 (0.93, 1.37) | 0.212 |
 FOS-based confirmatory pattern | ||||||
  No. of participants | 1042 | 1041 | 1041 |  | 3124 |  |
  No. of cases | 50 | 40 | 43 |  | 133 |  |
  Unadjusted | 1.00 | 0.79 (0.52, 1.21) | 0.86 (0.56, 1.30) | 0.435 | 0.90 (0.75, 1.06) | 0.180 |
  Model 1 | 1.00 | 0.78 (0.51, 1.19) | 0.84 (0.55, 1.27) | 0.378 | 0.90 (0.74, 1.06) | 0.179 |
  Model 2 | 1.00 | 0.88 (0.55, 1.40) | 0.81 (0.51, 1.27) | 0.354 | 0.88 (0.74, 1.07) | 0.144 |
Subclinical hypothyroidism | ||||||
 Native-based exploratory pattern | ||||||
  No. of participants | 1111 | 1111 | 1110 |  | 3332 |  |
  No. of cases | 89 | 129 | 123 |  | 341 |  |
  Unadjusted | 1.00 | 1.51 (1.14, 2.00) | 1.43 (1.08, 1.91) | 0.015 | 1.11 (0.99, 1.25) | 0.066 |
  Model 1 | 1.00 | 1.47 (1.11, 1.97) | 1.47 (1.10, 1.96) | 0.010 | 1.12 (1.00, 1.26) | 0.061 |
 Model 2 | 1.00 | 1.49 (1.11, 1.98) | 1.54 (1.41, 2.09) | 0.005 | 1.14 (1.01, 1.28) | 0.041 |
 EPIC-based exploratory pattern | ||||||
  No. of participants | 1110 | 1111 | 1111 |  | 3332 |  |
  No. of cases | 96 | 119 | 126 |  | 341 |  |
  Unadjusted | 1.00 | 1.27 (0.96, 1.68) | 1.35 (1.02, 1.79) | 0.036 | 1.13 (1.01, 1.26) | 0.041 |
  Model 1 | 1.00 | 1.23 (0.93, 1.64) | 1.34 (1.01, 1.78) | 0.043 | 1.13 (1.01, 1.27) | 0.037 |
  Model 2 | 1.00 | 1.27 (0.94, 1.71) | 1.44 (1.07 1.94) | 0.015 | 1.16 (1.03, 1.31) | 0.017 |
 FOS-based confirmatory pattern | ||||||
  No. of participants | 1111 | 1111 | 1110 |  | 3332 |  |
  No. of cases | 116 | 115 | 110 |  | 341 |  |
  Unadjusted | 1.00 | 0.98 (0.75, 1.29) | 0.94 (0.71, 1.23) | 0.643 | 0.99 (0.89, 1.11) | 0.871 |
  Model 1 | 1.00 | 0.94 (0.71, 1.24) | 0.92 (0.70, 1.22) | 0.568 | 0.99 (0.88, 1.11) | 0.858 |
  Model 2 | 1.00 | 0.96 (0.72, 1.28) | 0.92 (0.70, 1.24) | 0.592 | 1.00 (0.88, 1.12) | 0.936 |