Cardiometabolic-related dietary patterns and thyroid function: a population-based cross-sectional study

Table 3 Association between dietary pattern scores and thyroid stimulating-hormone, free thyroxine, and thyroid peroxidase antibodies in participants with normal thyroid function (n = 2991)^{a, b}

	Native− based exploratory pattern		EPIC− based exploratory pattern		FOS− based confirmatory pattern
	Β (95% CI)	p value	Β (95% CI)	p value	Β (95% CI)	p value
TSH, mU/L
Unadjusted	0.08 (0.04, 0.12)	< 0.001	0.06 (0.03, 0.10)	0.001	− 0.04 (− 0.08, 0.00)	0.051
Model 1^c	0.08 (0.04, 0.12)	< 0.001	0.06 (0.03, 0.10)	0.001	− 0.04 (− 0.08, 0.00)	0.049
Model 2^d	0.08 (0.05, 0.12)	< 0.001	0.07 (0.03, 0.10)	< 0.001	− 0.03 (− 0.07, 0.00)	0.069
FT4, ng/dL
Unadjusted	− 0.01 (− 0.01, 0.00)	0.060	− 0.01 (− 0.01, 0.00)	0.055	− 0.002 (− 0.01, 0.01)	0.595
Model 1^c	− 0.01 (− 0.01, − 0.001)	0.025	− 0.01 (− 0.01, − 0.001)	0.022	− 0.002 (− 0.01, 0.00)	0.516
Model 2^e	− 0.01 (− 0.01, 0.00)	0.066	− 0.01 (− 0.01, 0.00)	0.070	− 0.001 (− 0.01, 0.00)	0.625
TPOAb, U/L
Unadjusted	− 0.02 (− 0.06, 0.03)	0.459	− 0.02 (− 0.07, 0.02)	0.298	− 0.01 (− 0.05, 0.04)	0.690
Model 1^f	− 0.02 (− 0.06, 0.03)	0.487	− 0.02 (− 0.07, 0.02)	0.312	− 0.01 (− 0.05, 0.04)	0.704
Model 2^g	− 0.02 (− 0.06, 0.03)	0.491	− 0.02 (− 0.07, 0.02)	0.317	− 0.01 (− 0.05, 0.03)	0.669

^aExploratory patterns were derived using the reduced rank regression
^bEstimates were based on one standard deviation for each pattern
^cAdjusted for age (continuous), and sex
^dAdjusted for age (continuous), sex, smoking (never, current, former), education (< 6, 6–12, ≥ 12 years), having a full-time job (yes, no), and TPOAb positivity (yes, no)
^eAdjusted for age, sex, smoking (never, current, former), education (< 6, 6–12, and ≥ 12 years), having a full-time job (yes, no), marital status (married, others), family history of diabetes (yes, no), TPOAb positivity (yes, no)
^fAdjusted for sex
^gAdjusted for sex, energy intake (continuous), smoking (never, current, former), and having a full-time job (yes, no)

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