Table 3 Reproductive outcomes of first-cycle IVF-ET
| Â | Canalization defect vs. Control | Unification defect vs. control | ||||||
|---|---|---|---|---|---|---|---|---|
Control | Canalization defect | RR (95%CI) | aP value | Control | Unification defect | RR (95%CI) | aP value | |
Clinical pregnancy | 206 (62.0%) | 126 (38.0%) | 0.829 (0.690,0.997) | 0.046 | 263 (49.1%) | 182 (34.1%) | 0.813 (0.695,0.952) | 0.010 |
Ectopic pregnancy | 3 (1.4%) | 5 (4.0%) | 1.992 (0.486,8.168) | 0.543 | 6 (2.3%) | 5 (2.7%) | 1.247 (0.309,5.037) | 1.247 |
First-trimester pregnancy loss | 11 (5.3%) | 25 (19.8%) | 2.716 (1.393,5.295) | 0.003 | 20 (7.6%) | 36 (19.8%) | 3.288 (1.776,6.085) | 0.000 |
Second-trimester pregnancy loss | 4 (1.9%) | 8 (6.3%) | 2.091 (0.627,6.978) | 0.230 | 11 (4.2%) | 6 (3.3%) | 0.854 (0.288,2.532) | 0.776 |
 Singleton | 3 (1.4%) | 4 (3.2%) | 1.618 (0.370,7.086) | 0.523 | 6 (2.3%) | 5 (2.7%) | 1.176 (0.365, 3.793) | 0.786 |
 Twin | 1 (0.5%) | 4 (3.2%) | 3.621 (0.382,34.34) | 0.262 | 5 (1.9%) | 1 (0.5%) | 0.288 (0.034, 2.411) | 0.253 |
Live birth | 128 (38.6%) | 84 (25.3%) | 0.647 (0.513,0.815) | 0.000 | 219 (41.1%) | 132 (24.8%) | 0.713 (0.586,0.868) | 0.001 |
 Singleton | 86 (25.9%) | 65 (19.6%) | 0.706 (0.532, 0.938) | 0.016 | 145 (27.2%) | 117 (22.0%) | 0.712 (0.575, 0.883) | 0.002 |
 Twin | 42 (12.7%) | 19 (5.7%) | 0.378 (0.221,0.646) | 0.000 | 74 (13.9%) | 15 (2.8%) | 0.194 (0.113,0.333) | 0.000 |
Preterm birth | 23 (17.9%) | 15 (17.8%) | 0.875 (0.471,1.629) | 0.674 | 42 (19.2%) | 26 (19.7%) | 1.106 (0.619,1.975) | 0.733 |
 Singleton | 10 (7.8%) | 8 (9.5%) | 1.147 (0.411, 3.202) | 0.794 | 15 (6.9%) | 17 (12.9%) | 1.462 (0.612, 3.442) | 0.385 |
 Twin | 13 (10.1%) | 7 (8.3%) | 0.993 (0.287, 3.436) | 0.991 | 27 (12.3%) | 9 (6.8%) | 0.310 (0.074, 1.299) | 0.109 |