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Table 4 Stratified association between SII with all-cause, cardiovascular and cardio-cerebrovascular mortality by sex

From: Systemic immune-inflammation index (SII) and the risk of all-cause, cardiovascular, and cardio-cerebrovascular mortality in the general population

 

Tertile1

HR

Tertile2

HR (95% CI)

Tertile3

HR (95% CI)

P-value

Trend

All-cause mortality

 Female

1.00

1.108 (1.106, 1.110)*

1.553 (1.550, 1.555)*

 < 0.001

 Male

1.00

1.144 (1.143, 1.146)*

1.445 (1.443, 1.447)*

 < 0.001

Cardiovascular mortality

 Female

1.00

3.906 (3.885, 3.926)*

3.575 (3.556, 3.595)*

 < 0.001

 Male

1.00

0.688 (0.686, 0.691)*

1.243 (1.239, 1.247)*

 < 0.001

Cardio-cerebrovascular mortality

 Female

1.00

3.169 (3.153, 3.184)*

2.990 (2.975, 3.006)*

 < 0.001

 Male

1.00

0.723 (0.720, 0.725)*

1.084 (1.081, 1.088)*

 < 0.001

  1. CI confidence interval, HR hazard ratio, SII (Platelet count × Neutrophils)/lymphocytes
  2. Analysis was adjusted for age, gender, ethnicity, education, marital status, smoker, drinker, DM, hypertension, HF, CHD, stroke, cancer, BMI, hemoglobin, glycohemoglobin, platelets, blood urea nitrogen,urea acid, creatinine, cholesterol, glucose, LDL-C, HDL-C, triglyceride, albumin
  3. *P < 0.001