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Table 2 Multivariate Cox regression models between SII with all-cause, cardiovascular and cardio-cerebrovascular mortality

From: Systemic immune-inflammation index (SII) and the risk of all-cause, cardiovascular, and cardio-cerebrovascular mortality in the general population

 

Tertile 1

HR

Tertile 2

HR (95%CI) P-value

Tertile 3

HR (95%CI) P-value

All-cause mortality

 Model 1

1.00

0.985 (0.984, 0.985)*

1.423 (1.422, 1.424)*

 Model 2

1.00

1.037 (1.037, 1.038)*

1.422 (1.421, 1.423)*

 Model 3

1.00

1.108 (1.107, 1.109)*

1.479 (1.477, 1.480)*

Cardiovascular mortality

 Model 1

1.00

1.132 (1.130, 1.134)*

1.489 (1.487, 1.491)*

 Model 2

1.00

1.202 (1.201, 1.204)*

1.456 (1.454, 1.458)*

 Model 3

1.00

1.328 (1.325, 1.332)*

1.602 (1.597, 1.606)*

Cardio-cerebrovascular mortality

 Model 1

1.00

1.124 (1.122, 1.125)*

1.471 (1.469, 1.472)*

 Model 2

1.00

1.192 (1.190, 1.193)*

1.448 (1.446, 1.450)*

 Model 3

1.00

1.212 (1.209, 1.215)*

1.396 (1.393, 1.400)*

  1. CI Confidence interval, HR Hazard ratio, SII (Platelet count × Neutrophils)/lymphocytes
  2. Model 1was adjusted for none. Model 2 was adjusted for age, gender, ethnicity, education, marital status, smoker, and drinker. Model 3 was further adjusted for DM, hypertension, HF, CHD, stroke, cancer, BMI, hemoglobin, glycohemoglobin, platelets, blood urea nitrogen, creatinine, cholesterol, glucose, LDL-C, HDL-C, triglyceride, albumin
  3. *P < 0.00001