Serum growth differentiation factor-15 (GDF-15) is a biomarker of cardiac manifestations in children with COVID-19

Table 5 Statistical comparison according to ECHO findings and cardiac affection of studied children with COVID-19 as regards serum GDF-15 level

		Serum GDF-15 level (pg/ml)		Test value	P-value	Sig.
		Median (IQR)	Range	Test value	P-value	Sig.
ECHO	Abnormal	1008.38 (530.27–1445.38)	75.83–2940.2	− 4.089‡	< 0.001	HS
ECHO	Normal	342.06 (202.2–604.76)	47.47–1637.3	− 4.089‡	< 0.001	HS
Carditis	No	558.34 (265.32–873.16)	47.47–2940.2	− 3.814‡	< 0.001	HS
Carditis	Yes	1443.5 (1138.7–1676.44)	346.5–2335.44	− 3.814‡	< 0.001	HS
Ejection Fraction	Low	1443.5 (1038.84–2150.4)	119.11–2940.2	− 5.706‡	< 0.001	HS
Ejection Fraction	Normal	521.26 (236.26–638.6)	47.47–2335.44	− 5.706‡	< 0.001	HS
Cardiac affection	No	502.53 (235.92–604.76)	47.47–1017.04	− 6.425‡	< 0.001	HS
Cardiac affection	Yes	1444.44 (1074.28–2150.4)	119.11–2940.2	− 6.425‡	< 0.001	HS

ISSN: 2047-783X