Variables | Control (12127) | HI (541) | PH (440) | P Value |
---|---|---|---|---|
Age (year) | 70 (60–79) | 76 (68–82) | 78.5 (71–84) |  < 0.001 |
Male, % | 7532 (62.1) | 314 (58.0) | 254 (57.7) | 0.033 |
Medical history | ||||
 Hypertension, % | 7884 (65.0) | 363 (67.1) | 300 (68.2) | 0.250 |
 Diabetes mellitus, % | 2037 (16.8) | 92 (17.0) | 65 (14.8) | 0.529 |
 Hypercholesterolemia, % | 740 (6.1) | 26 (4.8) | 26 (5.9) | 0.460 |
 Atrial fibrillation, % | 1793 (14.8) | 178 (32.9) | 153 (34.8) |  < 0.001 |
 Previous ischemic stroke, % | 1572 (13.0) | 70 (12.9) | 69 (15.7) | 0.252 |
 Smoking, % | 3031 (25.0) | 111 (20.5) | 84 (19.1) | 0.001 |
Prior drugs use | ||||
 Prior antiplatelet use, % | 1749 (14.4) | 92 (17.0) | 94 (24.1) |  < 0.001 |
 Prior anticoagulant use, % | 169 (1.4) | 15 (2.8) | 11 (2.5) | 0.008 |
 Prior statin use, % | 1154 (9.5) | 43 (7.9) | 54 (12.3) | 0.068 |
 Baseline systolic pressure (mmHg) | 154 (140–168) | 158 (140–172) | 157 (143–170) | 0.001 |
 Baseline diastolic pressure (mmHg) | 85 (76–94) | 86 (77–96) | 86 (78–95) | 0.006 |
 Baseline NIHSS score | 5 (2–9) | 11 (5–16) | 12 (6–18) |  < 0.001 |
 OTT (min) | 149 (108–196) | 157 (115–207) | 155 (110–206) | 0.009 |
 Remote hemorrhage | NA | 163 (30.1) | 249 (56.6) |  < 0.001 |
Fibrinolytic drug | Â | Â | Â | 0.519 |
 rt-PA, % | 11920 (98.3) | 534 (98.7) | 435 (98.9) |  |
 Urokinase, % | 207 (1.7) | 7 (1.3) | 5 (1.1) |  |
7d mortality, % | 271 (2.2) | 42 (7.8) | 115 (26.1) |  < 0.001 |
Stroke recurred at discharge, % | 222 (1.8) | 11 (2.0) | 26 (5.9) |  < 0.001 |
Stroke recurred at 3Â m, % | 184 (1.5) | 6 (1.1) | 3 (0.7) | 0.259 |
mRS score at 90d | 1 (0–3) | 3 (1–5) | 5 (3–6) |  < 0.001 |