Fig. 2From: A mechanistic approach to prove the efficacy of combination therapy against New Delhi metallo-β-lactamases producing bacterial strain: a molecular and biochemical approacha Michaelis–Menten plot and b Lineweaver–Burk plot of nitrocefin hydrolysis by NDM-1 in the absence of any antibiotic, in the presence of 5 nM of streptomycin, in the presence of 5 nM of amikacin and in the presence of 5 nM each of streptomycin in combination with amikacin. 5 nM of NDM-1 was taken during the experiment. The study was done at 298 K using sodium phosphate buffer (50 mM) of pH 7.4Back to article page