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Table 2 Summary, biomechanical parameters: means and standard deviations of failure loads (N) and stiffness (N/mm) for femurs, tibiae and humeri, total and divided into subgroups of light (< 400 g) and heavy (> 400 g) animals

From: Whole bone testing in small animals: systematic characterization of the mechanical properties of different rodent bones available for rat fracture models

 

Failure load (N)

Failure load (N)

Light/heavy

p value failure load

Light/heavy

Failure load (N)

Δ right/left

Stiffness (N/mm)

Stiffness (N/mm)

Light/heavy

p value stiffness

Light/heavy

Stiffness (N/mm)

Δ right/left

Femur (n = 40)

 Light (N = 22)

175.4 ± 45.23

138.1 ± 16.38

< 0.0001

5.6 ± 3.91

315.6 ± 63.00

280.8 ± 59.85

< 0.0001

37.4 ± 24.68

 Heavy (N = 18)

221.0 ± 18.95

16.0 ± 6.91

358.1 ± 34.64

43.1 ± 16.22

Tibia (N = 40)

 Light (N = 22)

117.1 ± 33.94

89.6 ± 13.25

< 0.0001

9.8 ± 9.48

143.8 ± 36.99

120.7 ± 32.16

< 0.0001

18.7 ± 12.76

 Heavy (N = 18)

150.6 ± 16.14

9.4 ± 10.95

171.9 ± 18.28

17.2 ± 14.72

Humerus (N = 40)

 Light (N = 22)

124.6 ± 41.13

90.23 ± 6.97

< 0.0001

5.5 ± 5.09

260.5 ± 59.97

213.6 ± 35.06

< 0.0001

14.4 ± 7.04

 Heavy (N = 18)

166.5 ± 20.79

13.2 ± 7.58

317.7 ± 20.42

19.7 ± 15.92