Table 1 Lymphocytes and inflammatory factor changes before and after UCB infusion
Parameters | Before UCB infusion | After UCB infusion | P value |
|---|---|---|---|
CD3 + T-lymphocyte [M(IQR),/μl] | 1536.10 (894.08, 1658.14) | 1354.46 (1244.18, 1907.08) | 0.796 |
CD4 + T-lymphocyte [M(IQR),/μl] | 693.80 (203.59, 822.66) | 709.72 (639.38, 925.22) | 0.608 |
CD8 + T-lymphocyte [M(IQR),/μl] | 617.61 (376.96, 760.51) | 564.36 (1527.14, 925.19) | 0.796 |
CD19 + B-lymphocyte [M(IQR),/μl] | 0.35 (0.00, 0.76) | 0.00 (0.00, 0.38) | 0.590 |
CD16 + /56 + natural killer cell [M(IQR),/μl] | 163.67 (63.62, 177.130 | 520.45 (397.74, 659.55) | 0.020 |
total lymphocytes [M(IQR),/μl] | 1698.64 (963.24, 1837.78) | 2186.45 (1932.89, 2486.45) | 0.197 |
TNF-α[M(IQR), pg/ml] | 11.45 (9.51, 16.23) | 3.8 (3.8, 3.8) | 0.018 |
IL-6[M(IQR), pg/ml] | 17.70 (9.71, 32.95) | 5.1 (5.1, 5.1) | 0.018 |
IL-8[M(IQR), pg/ml] | 28.00 (17.08, 55.10) | 1.5 (1.5, 1.5) | 0.018 |
IL-10[M(IQR), pg/ml] | 8.78 (5.75, 10.26) | 0.4 (0.4, 0.4) | 0.018 |
IL-1β[M(IQR), pg/ml] | 5.00 (5.00, 5.63) | 0.7 (0.7, 0.7) | 0.009 |
PCT (mean ± SD, ng/ml) | 2.33 ± 3.43 | 0.21 ± 0.12 | 0.006 |