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Table 1 The parasite burden in different groups of treatment by various doses of FLZ

From: Determination of parasitic burden in the brain tissue of infected mice in acute toxoplasmosis after treatment by fluconazole combined with sulfadiazine and pyrimethamine

Groups

Last day (before death)

Untreated

11,084,800

FLZ 10 mg

1,629,200

P value

P < 0.009

Untreated

11,084,800

FLZ 20 mg

1,520,400

P value

P < 0.009

  1. The results of the mean and standard deviation of the quantity of DNA were obtained from three different treatment groups. The Kruskal–Wallis test was used for the comparison between the groups at the significance level of 0.05. The Mann–Whitney U test was used for multiple comparisons between the groups with the Bonferroni correction changing the significance level to 0.01 and 0.025. The parasite load of Toxoplasma tachyzoites in each of the two groups indicated a statistically significant difference