From: Clinical significance of dysregulation of miR-381 in pediatric acute myeloid leukemia
Parameters | Cases No. (n = 102) | miR-381 expression | P | |
---|---|---|---|---|
Low (n = 62) | High (n = 40) | |||
Age (years) | 0.840 | |||
> 6 | 45 | 28 | 17 | |
≤ 6 | 57 | 34 | 23 | |
Gender | 0.686 | |||
Male | 52 | 33 | 19 | |
Female | 50 | 29 | 21 | |
WBC counts (× 109/L) | ||||
> 10 | 52 | 31 | 21 | 0.841 |
≤ 10 | 50 | 31 | 19 | |
Leukocyte (/μl) | 0.316 | |||
> 10,000 | 47 | 26 | 21 | |
≤ 10,000 | 55 | 36 | 19 | |
FAB classification | 0.026 | |||
M1–M6 | 90 | 51 | 39 | |
M7 | 12 | 11 | 1 | |
Extramedullary disease | 0.420 | |||
Absent | 53 | 30 | 23 | |
Present | 49 | 32 | 17 | |
Cytogenetics | ||||
Favorable | 17 | 9 | 8 | |
Intermediate | 49 | 24 | 25 | 0.010 |
Unfavorable | 36 | 29 | 7 | |
Day 7 response to treatment | ||||
Favorable | 62 | 34 | 28 | 0.149 |
Unfavorable | 40 | 28 | 12 |