Table 5 Pooled proportions of the different pregnancy and perinatal outcomes identified in the present systematic review
Pregnancy outcome | SARS-CoV-2 | MERS-CoV | SARS-CoV | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Study (n) | Reports (n) | Pregnancies or neonate (n) | Pooled % (95%-CI) | Study (n) | Reports (n) | Pregnancies or neonate (n) | Pooled % (95%-CI) | Study (n) | Reports (n) | Pregnancies or neonate (n) | Pooled % (95%-CI) | |
PTB < 34 week | 11 | 61 | 682 | 8.9% [6.1–19.3] | 7 | 4 | 12 | 33.3% [14.2–38.9] | 7 | 3 | 25 | 12% [3.6–31.5] |
PTB < 37 week | 9 | 86 | 602 | 14.3% [9.2–33.2] | 7 | 0 | 12 | 0.0% [0.0–7.4] | 6 | 5 | 23 | 21.7% [7.4–44.6] |
>37 week | 13 | 317 | 686 | 46.2% [41.5–58.9] | 5 | 8 | 10 | 80% [44.2–97.8] | 7 | 5 | 13 | 38.5% [0.0–68.4] |
Preeclampsia | 5 | 9 | 159 | 5.7% [3.3–10.1] | 2 | 1 | 8 | 12.5% [0.0–53.6] | 2 | 0 | 2 | 0% [0.0–84.7] |
pPROM | 7 | 16 | 179 | 8.9% [5.5–14.6] | 2 | 0 | 2 | 0.0 [0.0–84.2] | 2 | 1 | 8 | 12.5% [0.0–53.8] |
FGR | 4 | 1 | 86 | 1.2% [0.0–6.3] | 4 | 0 | 6 | 0.0% [0.0–46.5] | 6 | 2 | 16 | 12.5% [2.2–38.6] |
Miscarriage | 2 | 1 | 41 | 2.4% [0.0–13.5] | – | – | – | – | 2 | 8 | 21 | 38.1% [18.7–62.5] |
ICU admission | 25 | 53 | 186 | 28.5%23.1–54.4] | 2 | 1 | 3 | 33.3% [1.2–91.3] | 2 | 12 | 22 | 54.5% [32.1–76.8] |
Maternal death | 4 | 8 | 523 | 1.5% [1.2–9.6] | 4 | 4 | 10 | 40% [12.5–74.3] | 3 | 3 | 24 | 12.5% [3.3–32.9] |
Cesarean delivery | 19 | 426 | 747 | 57.0% [48.9–78.8] | 6 | 6 | 9 | 66.7% [30.2–93.5] | 6 | 8 | 16 | 50% [25.6–75.9] |
Normal delivery | 11 | 192 | 662 | 29.0% [21.4–33.5] | 2 | 2 | 12 | 16.7% [2.4–48.6] | 4 | 4 | 18 | 22.2% [6.6–48.7] |
Perinatal outcome | ||||||||||||
Fetal distress | 7 | 14 | 56 | 25% [14.4–39.6] | 5 | 0 | 0 | 0.0% [0.0–52.3] | 5 | 4 | 12 | 33.3% [10.1–65.2] |
Apgar score < 7 | 7 | 1 | 72 | 1.4% [0.0–7.8] | 4 | 0 | 4 | 0.0% [0.0–60.1] | 5 | 0 | 5 | 0.0% [0.0–52.3] |
Neonatal asphyxia | 4 | 1 | 64 | 1.6% [0.0–8.9] | 3 | 0 | 3 | 0.0% [0.0–71.4] | 4 | 0 | 4 | 0.0% [0.060.8] |
Admission to NICU | 4 | 8 | 69 | 11.6% [5.4–22.6] | 3 | 1 | 3 | 33.3% [1.3–84.5] | 1 | 0 | 1 | 0.0% [0.0–98.5] |
Perinatal death | 8 | 5 | 430 | 1.2% [1.0–8.7] | 7 | 4 | 12 | 33.3% [10.6–65.3] | 6 | 1 | 10 | 10% [0.0–45.3] |
Vertical transmission | 25 | 0 | 1271 | 0.0 [0.0–1.5] | 7 | 0 | 12 | 0.0% [0.0–26.5] | 7 | 0 | 7 | 0.0% [0.0–41.6] |