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Table 4 Pooled proportions of the different maternal and postnatal outcomes and coexisting disorder identified in the present systematic review

From: The effect of coronavirus infection (SARS-CoV-2, MERS-CoV, and SARS-CoV) during pregnancy and the possibility of vertical maternal–fetal transmission: a systematic review and meta-analysis

Pregnancy and perinatal postnatal outcome

Study (n)

Number of reports

Pregnancies or neonate (n)

Pooled % (95%–CI)

Pregnancy outcome

 PTB < 34 week

25

68

719

9.5% [7.1–39.5]

 PTB < 37 week

22

91

637

14.3% [10.2–30.2]

 > 37 week

25

330

709

46.5% [41.2–56.3]

 Pre-eclampsia

9

10

169

5.9% [3.6–11.7]

 pPROM

11

17

183

9.3% [6.6–14.8]

 FGR

14

3

108

2.8% [1.8–8.9]

 Miscarriage

4

9

62

14.5% [7.7–26.5]

 ICU admission

29

66

211

31.3% [27.2–55.5]

 Maternal death

11

15

557

2.7% [1.4–14.6]

 Cesarean delivery

32

440

772

56.9% [48.2–78.9]

 Normal delivery

17

198

692

28.6% [22.4–41.6]

Prenatal outcome

 Fetal distress

17

18

68

26.5% [17.5–39.5]

 Apgar score < 7

16

1

81

1.2% [0.0–7.7]

 Neonatal asphyxia

11

1

71

1.4% [0.0–8.9]

 Admission to NICU

8

9

73

11.3% [5.6–20.3]

 Perinatal death

21

10

452

2.2% [1.2–12.8]

 Vertical transmission

39

0

1316

0.0% [0.0–1.0]

Coexisting disorders

 Hypertension

7

81

954

8.5% [7.1–17.4]

 Gestational diabetes

9

85

881

9.6% [6.6–20.7]

 Cardiovascular disease

2

27

470

5.7% [3.0–12.1]

 Digestive disease

3

4

111

3.6% [1.1–9.8]

 Asthma

4

44

794

5.5% [2.3–36.4]

  1. PTB preterm birth, pPROM preterm premature rupture of membranes, FGR fetal growth restriction, ICU intensive care unit, NICU neonatal intensive care unit